Human Fetal Testis Endoplasmic Reticulum Glucose-6-Phosphatase Enzyme Protein1
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چکیده
منابع مشابه
DIFFERENTIATION OF ENDOPLASMIC RETICULUM IN HEPATOCYTES II. Glucose-6-Phosphatase in Rough Microsomes
Electron microscope cytochemical localization of glucose-6-phosphatase in the developing hepatocytes of fetal and newborn rats indicates that the enzyme appears simultaneously in all the rough endoplasmic reticulum of a cell, although asynchronously within the hepatocyte population as a whole. To confirm that the pattern of cytochemical deposits reflects the actual distribution of enzyme sites,...
متن کاملThe microsomal glucose-6-phosphatase enzyme of pancreatic islets.
Microsomal fractions isolated from pancreatic islet cells were shown to contain high specific glucose-6-phosphatase activity. The islet-cell glucose-6-phosphatase enzyme has the same Mr (36,500), similar immunological properties and kinetic characteristics to the hepatic microsomal glucose-6-phosphatase enzyme.
متن کاملOn the Relationship of Liver Glucose-6-phosphatase to the Proliferation of Endoplasmic Reticulum in Phenobarbital Induction
The differentiated effects of phenobarbital treatment on liver microsomal enzymes have been further studied. The relationship between the resulting decrease in the specific glucose-6-phosphatase activity and the enhancement of formation of endoplasmic reticulum membranes with high drug-hydroxylating activity has been investigated with biochemical and histochemical methods. Biochemically and his...
متن کاملThe glucose-6-phosphatase system in human development.
The classical role of glucose-6-phosphatase in liver and kidney is the production of glucose for release into blood. In liver, glucose-6-phosphatase catalyses the terminal step of glycogenolysis and gluconeogenesis. Abnormally low hepatic glucose-6-phosphatase activity is found in human genetic deficiencies i.e. glycogen storage disease type I and in cases of developmental delay, found predomin...
متن کاملGlucose-6-phosphatase deficiency
Glucose-6-phosphatase deficiency (G6P deficiency), or glycogen storage disease type I (GSDI), is a group of inherited metabolic diseases, including types Ia and Ib, characterized by poor tolerance to fasting, growth retardation and hepatomegaly resulting from accumulation of glycogen and fat in the liver. Prevalence is unknown and annual incidence is around 1/100,000 births. GSDIa is the more f...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1996
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod55.2.298